Evaluation of Prelaminar Region and Lamina Cribrosa with Enhanced Depth Imaging Optical Coherence Tomography in Pseudoexfoliation Glaucoma

Abstract

Objectives: To analyze optic nerve head images of pseudoexfoliative glaucoma (PXG) patients and healthy volunteers obtained withenhanced depth imaging spectral domain-optical coherence tomography (SD-OCT).Materials and Methods: Seventy patients with PXG and 68 age- and gender-matched healthy subjects were included in thisprospective study. The prelaminar tissue and lamina cribrosa were imaged using spectralis OCT with the enhanced depth imagingtechnique. PXG disease stage was determined with visual field to evaluate relationships between prelaminar tissue thickness (PTT),lamina cribrosa thickness (LT) and disease severity.Results: There was no significant difference between the PXG group and control group with regard to age, gender, central cornealthickness, or axial length. The mean PTT (93.1±44.5 μm, p