Journals / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi / 2012 / Cilt: 21 - Sayı: 1

Böbrek naklinin geç dönemde kalp işlevleri ve yapısına etkisi

Effects of renal transplantation on cardiac function and morphology in the late posttransplant period

Pages
28–33
DOI
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Abstract

OBJECTIVE: To investigate the effects of renal transplantation on left ventricular (LV) function and morphology in patients with end-stage renal disease (ESRD) in the late posttransplant period.MATERIAL and METHODS: The prospective study included 40 patients (mean age 33.2 ± 7.7 years;25 female /15 male) with ESRD. In all of these patients, renal transplantation was performed successfully; and the serum creatinine levels were less than 2 mg/dL. The echocardiographic evaluations were performed before renal transplantation and 12. month after renal transplantation. Left ventricular diastolic diameter (LVDD), left ventricular systolic diameter (LVESD), left ventricular mass (LV Mass), left ventricular mass index (LVMI), LV ejection fraction (LVEF), Doppler and tissue Doppler parameters were obtained in all patients.RESULTS: At the twelfth month, LVDD (48 ± 5 vs 45 ± 6, p: 0.01), LVSD (33 ± 4 vs 29 ± 4, p< 0.001) LVMI (114 ± 31 vs 98 ± 13, p: 0.007) decreased significantly compared to the pretransplant period. There was a significant increase in the LVEF in at the twelfth month (59 ± 5 vs 67 ± 6, p< 0.001). There was a significant improvement between pretransplant period and late posttransplant period with regard to diastolic cardiac function.CONCLUSION: Renal transplantation had beneficial effects on diastolic and systolic functions and cardiac morphology in the late posttransplant period.

Özet

AMAÇ: Son dönem böbrek yetmezliği ile izlenen hastalarda nakil sonrası geç dönemde naklin sol ventrikül işlev ve yapısı üzerine etkisini araştırmayı planladık.GEREÇ ve YÖNTEMLER: 25 kadın /15 erkek olmak üzere 40 son dönem böbrek yetmezliği hastası ile yapılan bu ileri dönük çalışmada tüm hastalara başarılı bir şekilde böbrek nakli yapılmıştır (Tüm hastaların kreatin değerleri (