Does Dry Eye Affect Repeatability of Corneal Topography Measurements?

Abstract

Objectives:The purpose of this study was to assess the repeatability of corneal topography measurements in dry eye patients and healthy controls.Materials and Methods: Participants underwent consecutive corneal topography measurements (Sirius; Costruzione Strumenti Oftalmici,Florence, Italy). Two images with acquisition quality higher than 90% were accepted. The following parameters were evaluated: minimumand central corneal thickness, aqueous depth, apex curvature, anterior chamber volume, horizontal anterior chamber diameter, iridocornealangle, cornea volume, and average simulated keratometry. Repeatability was assessed by calculating intra-class correlation coefficient.Results: Thirty-three patients with dry eye syndrome and 40 healthy controls were enrolled to the study. The groupswere similar in terms of age (39 [18-65] vs. 30.5 [18-65] years, p=0.198) and gender (M/F: 4/29 vs. 8/32, p=0.366). Intraclasscorrelation coefficients among all topography parameters within both groups showed excellent repeatability (>0.90).Conclusion: The anterior segment measurements provided by the Sirius corneal topography system were highly repeatable for dry eyepatients and are sufficiently reliable for clinical practice and research.