Journals / Türkiye Tıp Dergisi Dahili Tıp Bilimleri / 1999 / Cilt: 6 - Sayı: 1
Intraerythrocytic magnesium levels of type 2 diabetes mellitus (NIDDM) patients with and without hypertension
- Pages
- 24–28
- DOI
- —
Abstract
In recent etiologic studies of essential hypertension and NIDDM, changes in magnesium (Mg++) metabolism we¬re attracted attention. We planned to investigate the intraerytrocytic~Mg++ levels in hypertensive and nonhyper-tensive diabetes mellitus patients. Twenty-four NIDDM patients without hypertension (9 males, 15 females, me¬an age 52+11,4), 26 NIDDM plus hypertension patients (10 males, 16 females, mean age 54±11.7) and 20 he¬althy controls (8 males, 12 females, mean age 51+10.05) were evaluated for intraerytrocytic Mg++ levels, the re¬sults were 4.9+-0.7 mg/dl, 4.8+0.65 mg/dl, 5.8+0.9 mg/dl, respectively. Mann-Whitney U test were used to com¬pare the groups. Mg++ levels of NIDDM patients with and without hypertension was not significantly different . (p>0.05), whereas both groups have significantly low levels of intraerytrocytic Mg++ when compared to control group (p
Özet
Sonyillarda esansiyel hipertansiyon ve tip 2 diabetes mellitusun (NIDDM) etyolojisine yonelik gahsmalaryapi-hrken, her iki hastahkta magnezyum (Mg++) metabolizmasmdaki degisiklikler arastirmacilann dikkatini gek-> mistir. Biz de hipertansif olan ve olmayan NIDDM'li hastalarda intraeritrositerMg++ duzeylerini arastirdik. Hi¬pertansif olmayan 24 NIDDM'li hasta (9 erkek, 15 kadin, yas ortalamasi 52±11.4) ve hipertansif NIDDM'li 26 hasta (10 erkek, 16 kadin, yas ortalamasi 54±11.7) ve 20 saglikh k'ontrol grubu (8 erkek, 12 kadin, yas orta¬lamasi 51±10.05) gahsmamiza alindi ve hepsinde intraeritrositer Mg++ seviyesi olguldu. Ortalama degerler si-rasiyla 4.9±0.7 mg/dl, 4.8+0.65 mg/dl, 5.8±0.9 mg/dl olarak saptandi. SonuglarMann-Whitney Utesti tie kar-silastmldi. Hipertansif olan ve olmayan NIDDM'li hastalar arasmda intraeritrositer Mg++ seviyesi agismdcm anlamli bir farklilik yoktu (p>0.05). Hipertansif olsun ya da olmasm NIDDM'li iki grubun saglikh kontrol gru¬bu He karsilastirmasmda, serum Mg++ seviyesi NIDDM'li hastalarda anlamli olarak dilsiik olarak bulundu (p