Journals / Türkiye Tıp Dergisi Dahili Tıp Bilimleri / 2002 / Cilt: 9 - Sayı: 4
The prevalences of HBV, HCV and HIV infection in patients with familial Mediterranean fever
- Pages
- 141–144
- DOI
- —
Abstract
Objective: In this study, we aimed to determine the prevalences of HBV, HCVand HIVinfection retrospectively in patients with familial mediterranean fever (FMF). Method: 74patients (73 male and !female with the mean age of 22.47 ± 3.56) and, age and sex matched 58 healthy persons for control group were included in this study. Serum HBsAg, anti-HBs, anti-HCV and anti-HIV levels were measured with Enzyme Immunoassay (EIA). Results: In patients group, HBsAg, anti-HCV, and anti-HIVpositivity were not found in any patient (0/74, 0/73 and 0/73, retrospectively). Anti-HBs positivity were found 4.84% (3/62). Although HBsAg, anti-HCV, and anti-HIV positivity were not found in the control group, anti-HBs positivity were found 16% (8/50). There was no statistically difference f or anti-HBs positivity between patient and control groups (p> 0.05).Conclusion: In conclusion, absence of any difference between the patient and healthy groups in view of HBsAg, anti-HBs, anti-HCV arid anti-HIVpositivity reveals that these agents do not imply in the pathogenesis of FMF.
Özet
Amaç: Bu çalışmada, ailesel akdeniz ateşi (AAA) olgularında hepatit B virüsü (HBV), hepatit C virüsü (HCV) ve "human immunodeficiency virus (HIV)" infeksiyonu prevalanslannı retrospektif olarak araştırmayı amaçladik.Yöntem: Çalışmaya 74 hasta (73'ü erkek, Ti kadın, ortalama yaş 22.47 ± 3-56yıl) ile, kontrol grubu olarak yaş ve cinsiyet uyumlu 58 sağlıklı birey alındı. Serum HBsAg, anti-HBs, anti-HCVve anti-HIV düzeyleri "Enzyme Immunoassay (EIA)" yöntemi ile araştırıldı. Bulgular: Hasta grubunda HBsAg (0/74), anti-HCV (0/73) ve anti-HIV (0/73) hiçbir hastada saptanmadı. Anti-HBs ise 62 hastanın 3 (%4.84)'ünde tespit edildi. Kontrol grubunda HBsAg (0/58), anti-HCV (0/58) ve anti-HIV (0/54) hiçbir olguda saptanmazken, anti-HBs 50 bireyin 8 (%16)'inde tespit edildi. Anti-HBspozitifliği açısından hasta ve kontrol grubu arasında istatistiksel olarak anlamlı farklılık yoktu (p> 0.05). Yorum: Sonuç olarak, AAA olan hastalarda HBsAg, anti-HBs, anti-HCV ve anti-HIVprevalanslarının sağlıklı kişilerdekinden farklılık göstermemesi, bu etkenlerin AAA etyopatogenezi ile ilişkili olamayacağını ortaya koymaktadır.