Osteoporosis in patients with long standing rheumatoid arthritis

Abstract

Our aim was to analyse bone mineral density (BMD), frequency of osteoporosis and to investigate the risk factors for bone loss in female patients with long standing rheumatoid arthritis (RA). BMD was measured at lumbar spine and femoral neck by dual-energy x-ray absorptiometry (DEXA) in 37 RA patients and in 30 healty age and sex matched control group. The frequency of osteoporosis in the RA patients was 35.1% at lumbar spine and 32.4% at femoral neck. Seventy-eight % of the RA patients were in postmenopausal period. Their mean age was 59.4 years, disease duration was 9.6 years. The frequency of bone loss in the RA patients was statistically high according to the control group (p

Özet

Bu çalışmanın amacı uzun süreli romatoid artrit (RA)’sı olan kadın hastalarda kemik mineral yoğunluğu (KMY)’yi ölçmek, osteoporoz (OP) sıklığını ve risk faktörlerini araştırmak idi. KMY 37 RA’lı kadın hastada ve uygun yaşta 30 sağlıklı kadında lomber omurga ve femur boynundan Dual Energy X-ray Absorpsiyometri (DEXA) kullanılarak ölçüldü. RA’lı hastalardaki osteoporoz sıklığı lomber omurgada %35,1 ve femur boynunda %32,4 idi. RA’lı hastaların %78’i postmenopozal dönemde idi. Hasta grubunda yaş ortalaması 59,4 yıl, hastalık süresi 9,6 yıldı. RA'lı grupta lomber omurga ve femur boynu KMY'si kontrol grubuna göre anlamlı olarak düşüktü (p