Frequency of anemia of chronic disease in patients with Behcet's disease

Demet ÇİÇEK, Betül DEMİR, Başak KANDİ, Bakar Selma DERTLİOĞLU, Nevin İLHAN

Abstract

Anemia of chronic disorders is a mild to moderate anemia characterized by decreased serum iron, decreased total iron-binding capacity and increased iron stores. Anemia of chronic disorders occurs in a wide variety of diseases including cancer, chronic infections and inflammatory disorders. Behcet’s disease is a chronic and inflammatory disease. There is a possibility of anemia of chronic disorders in Behcet’s disease. But, frequency of anemia of chronic disorders in Behcet’s disease was never evaluated in previous studies. Thus, we aimed to determine the frequency of anemia of chronic disease in Behcet’s disease. Material and Method: The study included 40 patients with Behcet’s disease and 20 healthy volunteers. Serum iron, hemoglobin, ferritin, UIBC and TIBC levels were assessed. Anemia was determined as hemoglobin levels

Özet

Kronik hastal›k anemisi (KHA); serum demir, total demir ba¤lama kapasitesinde azalma ve demir depolar›nda art›fl ile seyreden, hafif-orta fliddette bir anemi tablosudur. Kanserler, inflamatuvar hastal›klar ve kronik infeksiyonlar gibi çeflitli hastal›klarda KHA görülebilir. Kronik seyirli ve inflamatuvar bir hastal›k olan Behçet hastal›¤›nda KHA geliflmesi olas› görünmektedir. Önceki çal›flmalarda Behçet hastal›¤›nda KHA s›kl›¤› hiç de¤erlendirilmemifltir. Bu nedenle çal›flmam›zda Behçet hastalar›nda KHA’y› araflt›rmay› amaçlad›k. Gereç ve Yöntem: Çal›flmaya 40 Behçet hastas› ile 20 sa¤l›kl› gönüllü al›nd›. Hastalar›n serum demir, hemoglobin, ferritin, doymam›fl demir ba¤lama kapasitesi (unsaturated iron binding capacity (UIBC)) ve total demir ba¤lama kapasitesi (total iron binding capacity (TIBC)) de¤erleri ölçüldü. Behçet hastalar› ve kontrol grubunda erkek için