Coexistence of disseminated granuloma annulare and asymptomatic multiple myeloma

Şebnem AKTAN, Sevgi AKARSU, Abdullah KATGI, Banu LEBE, Ceylan AVCI CANBAZ, Güner ÖZSAN GAYRİ

Abstract

Granuloma annulare (GA), which is characterized by necrobiotic dermal papules, is a benign inflammatory dermatosis of unknown cause. Several morphologic forms of GA, including localized, disseminated, linear, nodular, perforating, subcutaneous, pustular, and arcuate dermaerythema have been reported in the literature. Disseminated GA, a rarely seen form, has been reported to be in association with some hematopoietic and solid malignancies, however, it has been suggested that the exact causative relationship between malignancy and GA is unclear. We present here a 66-year-old female patient with disseminated GA associated with asymptomatic multiple myeloma. (Turkderm 2013; 47: 121-418-21)

Özet

Granüloma anulare (GA) nekrobiyotik dermal papüller ile karakterize, nedeni bilinmeyen, benin, inflamatuvar bir dermatozdur. Literatürde lokalize, dissemine, lineer, nodüler, perforan, subkutanöz, püstüler ve arkuat dermal eritem gibi değişik morfolojik formları bildirilmiştir. Nadir görülen dissemine GA formunun bazı hematopoetik veya solid malignitelerle birlikteliği bildirilse de, malignite ile GA arasındaki kesin nedensel ilişkinin belirsiz olduğu ileri sürülmüştür. Burada asemptomatik multipl myelomun eşlik ettiği dissemine GAlı 66 yaşında bir kadın olgu sunulmaktadır. (Türkderm 2013; 47: 176-9)