Evaluation of Post-operative Meningitis: Comparison of Meningitis Caused by Acinetobacter spp. and Other Possible Causes

Abstract

AIM: To analyse postoperative meningitis (POM) after craniotomy, and to compare the clinical characteristics, treatment outcomesand mortality rates of POM that were caused by Acinetobacter spp. or other possible causes.MATERIAL and METHODS: In this study, POM cases in our hospital between 2008 and 2016 were retrospectively reviewed. Caseswere divided into three groups; Acinetobacter spp. meningitis (case group), non-Acinetobacter bacterial meningitis (control group1) and culture negative meningitis (control group 2). Demographic, clinical, laboratory features, treatment modalities and mortalityrates were compared between case and control groups.RESULTS: A total of 112 patients with POM were included in the study. Cerebrospinal fluid (CSF) culture results were negativein 50 (44.6%) patients; bacteria were isolated from CSF of 62 (55.3%) patients. Acinetobacter spp. was isolated from 28 (45%)patients, while bacteria other than Acinetobacter spp. were detected in 34 (55%) patients. No significant differences were observedbetween case and control groups in terms of age, gender, comorbidity and operation type. For the case group, change of treatmentaccording to culture result was significantly different from control groups (p