Preoperative Systemic Inflammatory Markers in Different Brain Pathologies: An Analysis of 140 Patients

Abstract

AIM: To analyze preoperative inflammatory markers including neutrophil, lymphocyte and platelet counts and neutrophil tolymphocyte (NLR) and platelet to lymphocyte (PLR) ratios in a group of patients with different brain pathologies and healthy controls.MATERIAL and METHODS: Above mentioned preoperative inflammatory markers were analyzed in a total of 140 patients included39 with temporal lobe epilepsy, 37 with glioblastoma multiforme, 32 with grade-I meningioma and 32 with intracranial metastasis.Healthy controls included 30 subjects. The levels were compared between each patient group and between patients and controls.RESULTS: Significant higher neutrophil, platelet counts, NLR and PLR were found in glioma, meningioma and metastasis patientscompared to epilepsy (p