Detection of gastroesophageal reflux in children with cerebral palsy using combined multichannel intraluminal impedance- ph procedure

Abstract

Çaltepe G, Yüce Ö, Comba A, Özyürek H, Kalaycı AG, Taşdemir HA. Detection of gastroesophageal reflux in children with cerebral palsy using combined multichannel intraluminal impedance-pH procedure. Turk J Pediatr 2016; 58: 524-531.Gastroesophageal reflux (GER) is a very common condition in children with neurological impairment and this can influence nutritional and respiratory outcomes. The aim of this study was to investigate the presence of GER in children with cerebral palsy (CP) using multiple intraluminal impedance (MII)-pH monitoring. The use of combined MII-pH allows for the detection of both acid and non-acid reflux episodes. A total of 29 CP patients with symptoms suggesting GER, aged 2 to 10 years old, underwent 24-hour combined MII-pH monitoring. There were a total of 3899 reflux episodes, of which 29% were acid, 60% were weakly acid and 11% were alkaline. The number of non-acid reflux episodes was statistically significantly greater (p