Increasing vitamin D deficiency in children from 1995 to 2011

Chan-Hoo PARK, Hyang-Ok WOO, Hee-Shang YOUN, Jae-Young LİM, Ji-Hyun SEO, Hye Jin CHUNG, Hye-Jung KİM, Jung Sook YEOM, Ji Sook PARK, Eun-Sil PARK, Jun-Je PARK

Abstract

Seo JH, Chung HJ, Kim HJ, Yeom JS, Park JS, Park ES, Lim JY, Park CH, Woo HO, Youn HS, Park JJ. Increasing vitamin D deficiency in children from 1995 to 2011. Turk J Pediatr 2016; 58: 616-622.Serum concentrations of 25-hydroxy vitamin D3 [25(OH)D3] and vitamin D deficiency have changed over time in Korean children. This study assessed serum 25(OH)D3 concentrations and the prevalence of vitamin D deficiency in children. Serum samples were obtained during 1995 to 2011, and 25(OH)D3 concentrations were measured by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Tests of 948 serum samples showed that median 25(OH)D3 concentrations decreased significantly (P