Establishing reference values for amplitude-integrated electroencephalography in preterms below 35 weeks of gestational age: A prospective observational cohort study

Abstract

Han YM, Lee NR, Bae MH, Park KH, Lee YJ, Nam SO, Byun SY.Establishing reference values for amplitude-integrated electroencephalographyin preterms below 35 weeks of gestational age: A prospective observationalcohort study. Turk J Pediatr 2016; 58: 592-601.Characteristic patterns in amplitude-integrated electroencephalography (aEEG)develop with gestational age (GA), and so can be used to evaluate brainmaturation in premature infants. Reference aEEG values in normal preterminfants have not been identified and data are scarce. We aimed to validate acurrently available aEEG scoring system. We also investigated the developmentof aEEG activity during the first week after birth, determining referencevalues in preterm infants with no abnormal cranial ultrasound findings. Weprospectively studied aEEG and cranial ultrasounds in infants with a GA of