The role of soluble urokinase plasminogen activator receptor (SuPAR) as an indicator of the severity of acute pancreatitis

İbrahim KILINÇ, Adnan KARAİBRAHİMOĞLU, Başar CANDER, Sedat KOÇAK, Alpay TUNCAR, Mehmet ERGİN, Mehmet GÜL, Zerrin Defne DÜNDAR, Tamer ÇOLAK, Abdullah Sadık GİRİŞGİN, Kadir KÜÇÜKCERAN

Abstract

Background/aim: Soluble urokinase plasminogen activator receptor (suPAR) has been reported to have a positive correlation with theactivation degree of the immune system. This study’s aim is to investigate the efficiency of SuPAR serum levels in acute pancreatitis (AP)patients in determining the severity of disease.Materials and methods: This prospective research involves patients who arrived at the emergency service, were over 18 years old, hadnontraumatic abdominal pain and diagnosis of AP, and agreed to join the study. Demographic characteristics, contact information,laboratory and imaging test parameters, Ranson’s criteria, the Balthazar Severity Index, the Rapid Acute Physiologic Score (RAPS), andthe modified Glasgow (Imrie) score of all patients were recorded. Two study groups were created as score of