Human immunodeficiency virus and tuberculosis coinfection: clinical features and predictors of mortality

Abstract

Background/aim: This study was undertaken to identify subjects with human immunodeficiency virus and tuberculosis (HIV/TB)coinfection in a group of HIV-positive patients followed at five different healthcare centers, and to determine the demographic andclinical characteristics of these subjects as well as the predictors of mortality.Materials and methods: A database search for subjects with TB coinfection was performed among 1475 HIV-positive adult patients anda total of 66 individuals were identified with HIV/TB coinfection.Results: There were 66 patients (4.5%) with TB coinfection. Twenty-one percent (n = 14) of the patients with TB coinfection diedduring the study period and these patients had significantly lower baseline CD4 counts at the time of TB diagnosis (P = 0.005). Noneof the patients with CD4 count of ≥200 cells/mm3 died during follow-up and a low CD4 count at the time of TB diagnosis (