High neutrophil-to-lymphocyte ratio predicts acute allograft rejection in kidney transplantation: a retrospective study

Abstract

Background/aim: Our research focused on the identification of easily available and sensitive markers for early prediction of acutekidney allograft rejection (AR). We aimed to investigate the association between neutrophil-to-lymphocyte ratio (NLR) and AR inkidney transplant patients.Materials and methods: The medical records of 51 kidney transplant patients [12 female/39 male; median age of 32 (IQR: 24–44) years]were evaluated retrospectively. We considered a cut-off value of >2.5 as high NLR.Results: A total of 22 biopsy-proven AR patients and 29 controls were evaluated. The AR group had a higher NLR compared to thecontrols (P 2.5) are associated with AR in kidney transplant patients, leading to theconclusion that NLR might be an easily available and useful marker option for detection of AR in this patient population.