Factors associated with severe lung disease in an adult population with cystic fibrosis: a single-center experience

Abstract

Background/Aim: The patients with cystic fibrosis (CF) are living longer compared to the past, but respiratory failure is still the mostcommon cause of mortality. The aim of this study is to investigate factors associated with severe lung disease in a cohort of adult patientswith CF.Materials and methods: Demographic data, clinical and laboratory findings of the patients aged 18 years and more were collected andthe patients were grouped according to forced expiratory volume in 1 s (FEV1) as severe group: