Journals / Turkish Journal of Endocrinology and Metabolism / 2019 / Cilt: 23 - Sayı: 1
Evaluation of the Circulating Betatrophin Concentration and its Possible Correlations Among Diabetic Patients with Dyslipidemia
- Pages
- 1–7
- DOI
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Abstract
Objective: The circulating betatrophin levels in diabetic patients, treated with insulin or with oral hypoglycemic agents,were measured. The correlation between betatrophin levelsand the glucose/lipid variables was also analyzed.Material and Methods: Thirty-six diabetic patients (18 insulin-treated and 18 oral hypoglycemics-treated) and 16age-and sex-matched non-diabetic controls were enrolled.The serum levels of betatrophin, glucose, and lipids weremeasured.Results: The serum betatrophin levels were significantlylower in both the insulin-treated and oral hypoglycemicstreated diabetics compared to the controls (32.8±3.6 and48.4±5.2 vs. 54.4±3.7, respectively, p
Özet
Amaç: İnsülin veya oral hipoglisemik ajanlarla tedavi edilen diyabetik hastalarda dolaşımdaki betatrofin seviyeleri ölçüldü. Ayrıca, betatrofin seviyeleri ile glukoz/lipit değişkenleri arasındaki korelasyon analiz edildi. Gereç ve Yöntemler: Otuz altı diyabetik hasta (insülinle tedavi edilen 18 ve oral hipoglisemik ile tedavi edilen 18), yaş ve cinsiyeti eşleştirilmiş 16 diyabetik olmayan kontrol çalışmaya dâhil edildi. Serum betatrofin, glukoz ve lipit seviyeleri ölçüldü. Bulgular: Serum betatrofin düzeyleri hem insülinle hem de oral hipoglisemikle tedavi edilen diyabetiklerde kontrollere kıyasla anlamlı derecede düşük bulundu (sırasıyla 32,8±3,6 ve 48,4±5,2’ye karşı 54,4±3,7, p