Improving the sensitivity and accuracy of microcantilever biosensors by a truss structure within air medium

Abstract

Early diagnosis is a very fundamental issue in treating most diseases and for this purpose microcantileversare very effective and reliable devices. In this work, four models of biosensor-based microcantilever are compared anda novel design with high sensitivity, quality factor, and accuracy is proposed. A truss structure is designed near theanchored end of the microcantilever, which improves the sensitivity in order to increase detection accuracy. A linearrelationship between resonance frequency shift and masses has been estimated for all the designs. High quality factor,which increases the accuracy of measurement, is taken into account as the other benefit of the proposed design. Thesemicrocantilevers can be used as an array for multiple early diagnosis of cancer and moreover these features will improveclinical applications of cantilever sensors for early disease diagnosis