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Journals / Turkish Journal of Chemistry / 2002 / Cilt: 26 - Sayı: 1

Synthesis, Characterization and Biological Activity of Triorganotin Carboxylates Containing Germanium

Abdul MALIK, Saqib ALI, Muhammad MAZHAR, Muhammad Aziz CHOUDHARY, Umm-e SALMA, Saima ASHRAF

Pages
125–131
DOI
—

Abstract

Some new triorganotin carboxylates containing germanium with general formulae (R1GeCHR2CH2COO) Sn(CH2C(CH3)3)3 where R1 = N(CH2CH2O)3 and C6H5, R2 = C6H5, p-C6H4OCH3 and o-/p-C6H4F were synthesized and characterized by elemental analysis, infrared, multinuclear (1H, 13C, 119Sn) NMR and mass spectrometry. Antibacterial activity of these compounds was evaluated against the standard drugs ampicilline and amoxicilline, and found to be more active in some cases than the standard drugs.

Özet

Some new triorganotin carboxylates containing germanium with general formulae (R1GeCHR2CH2COO) Sn(CH2C(CH3)3)3 where R1 = N(CH2CH2O)3 and C6H5, R2 = C6H5, p-C6H4OCH3 and o-/p-C6H4F were synthesized and characterized by elemental analysis, infrared, multinuclear (1H, 13C, 119Sn) NMR and mass spectrometry. Antibacterial activity of these compounds was evaluated against the standard drugs ampicilline and amoxicilline, and found to be more active in some cases than the standard drugs.

Keywords: Turk. J. Chem., 26, (2002), 125-132. Full text: pdf Other articles published in the same issue: Turk. J. Chem., vol.26, iss.1.