Some bioactive organotin(IV) derivatives with 3,4-dichlorophenylacetic acid: synthesis, spectroscopic properties, and X-ray structure of [$Sn_4(C_4H_9)_8$(OOCC$H_2C_6H_3CI_2$)4O2 ]

Abstract

Some bioactive organotin(IV) derivatives of 3,4-dichlorophenylacetic acid (HL) were synthesized by reacting the ligand acid with various di- or tri-organotin compounds (in suitable mole ratios) in the presence of triethylamine. The structural investigation was carried out via multinuclear ( $^1H, ^{13}C,$ and $^{119}Sn$) NMR, IR spectroscopy, and X-ray crystallography. The crystal structure of 4 comprises a central $Sn_2O_2$ core with O atoms bonded to 2 dibutylbis(3,4-dichlorophenylacetato)tin(IV) units. All the Sn atoms of 4 are essentially 5-coordinated in distorted trigonal-bipyramidal geometry. Some of the compounds exhibited significant antibacterial and antifungal activity.