Can QT dispersion predict multi-vessel coronary artery disease in patients with acute coronary syndrome?

Abstract

Objectives. This study was planned to evaluate the relation between QT dispersion (QTd) and multi-vesselcoronary artery disease in acute coronary syndrome. Methods. Two hundreds and twenty-five consecutivepatients with a diagnosis of non-ST segment elevation acute coronary syndrome were included. Three groupswere defined as a single vessel, two vessels, and three vessels. Echocardiographic, biochemical andelectrocardiographic parameters of the groups were compared. Results. QTd, corrected QT dispersion (QTcd)and corrected QT max values significantly increased in patients with the three-vessel disease compared to thepatients in the single-vessel disease group (60±27 vs. 45±28 ms, 68±32 vs. 50±32 ms and 471±52 vs. 443±48ms; p=0.002, p=0.001, and p=0.001, respectively). Also, QTd and QTcd were statistically more increased inpatients with the two vessels disease than single-vessel disease group (57±29 vs. 45±28 ms; p=0.045, and63±32 vs. 50±32 ms; p=0.046, respectively). Conclusion. In a patient with acute coronary syndrome and diffusevessel disease, changes in the myocardial cells due to ischemia cause more of the QT dispersion in the patientswith a multi-vessel disease than those with single-vessel disease.