Synthesis of $alpha$-aminonitriles catalyzed by montmorillonite K10 in the presence of dicationic phosphonium salt in water under ultrasonic effect

Abstract

The synthesis of $alpha$-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S) − $alpha$-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.