How Should Helicobacter Pylori Infection Be Diagnosed by Endoscopy? Is It Enough to Have Received a Biopsy?

Abstract

Objective: To demonstrate the effectiveness of standardizing the endoscopic gastric biopsy site and sufficient quantity of biopsies in the detection of Helicobacter pylori (HP) infection, lymphoid aggregates, and gastrointestinal metaplasia. Methods: Having undergone gastroscopy due to dyspeptic complaints, 146 patients were included in the study. The data of the study were collected retrospectively. The patients whose biopsies were taken from two stomach regions, namely the corpus and antrum, were included in the study. Results: There were 58 (39.7%) patients with HP infection detected in the biopsies taken from the antrum and 57 (39%) patients with HP infection detected in the biopsies taken from the corpus. In total, there were 74 (50.7%) patients with HP positive. Sensitivity and specificity for antral biopsy were 78% and 100%, respectively. As for the corpus, the values were 77% and 100%, respectively. When the biopsy results of patients with lymphoid aggregate and intestinal metaplasia in one and both regions were compared, the p-values were found to be