Serum Endocan Levels in Patients with Retinal Vein Occlusion

Abstract

Purpose: We aimed to evaluate the serum Endocan (endothelial cell-specifi c molecule-1, ESM-1) levels in patients with retinal vein occlusion (RVO) and compare them with those of the control group to determine the correlation with illness activity Materials and Methods: Venous blood samples were obtained from 43 patients with RVO and 43 healthy subjects who attended Atatürk University Medical Faculty Eye Diseases Policlinic between 1 June 2015 and 1 September 2015. Thirty-one of the 43 patients had branch RVO, and 12 of the patients had central RVO. Results: The mean age of the patients was 62±10,19, and the mean age of the control group was 60,27±5,53. Twenty-four of the 43 patients (54,5%) suffered from RVO in their right eyes, and 19 of the patients (43,2%) suffered from RVO in their left eyes. No statically signifi cant differences in age and sex were observed between the patients and the control group. All patients had hypertension, and 15 patients had diabetes mellitus. Thirty 30 patients (68,2%) had ischemic-type RVO, 13 patients (29,5%) had nonischemic-type RVO. Thirty-one patients (70,5%) had branch RVO, and 12 patients (27,3%) had central RVO. Statically signifi cant differences in serum level of ESM-1 were observed between the patients and the control group (p