Evaluation of serum perlecan levels in pregnancy with mild and severe preeclampsia

Abstract

In this study, we aimed to determine the levels of perlecan contributing to autophagy inhibition and angiogenesis in severe and mild preeclamptic women. A total of 89 patients including severe preeclampsia, group 1 (n:30), mild preeeclampsia, group 2 (n:30) and control group, group 3 (n:29) were included in the study. All three groups were evaluated in terms of perlecan levels. Perlecan level in group 1 was determined at higher levels than other groups, and this level difference was statistically significant compared to the other two groups (p