Histopathological evaluation of endometrial sampling in different age groups - 1374 cases

Endometriyal örneklerin farklı yaş gruplarında histopatolojik değerlendirmesi - 1374 olgu

Abstract

The aim of this study was to evaluate the relationship between histopathological results and endometrial sampling and to iden- tify specific pathologies in different age groups. The histopatho- logical results of 1374 cases registered in our pathology archives, in whom endometrial sampling was performed in our hospital for various reasons between 2013 and 2014 were evaluated. Biopsy indications included menometrorrhagia (80.5%), postmenopau- sal bleeding (6.8%), myoma uteri (1.7%), cervical polyp (2.4%),infertility (0.2%), and hyperplasia/malignancy (8.4%). Histopat- hological diagnoses in order of frequency included endometrial polyp (37.2%), proliferation/secretion/menstrual phase (29.3%), irregular proliferative endometrium (8.4%), insufficient biopsy material (8.4%), endometritis (5.8%), stroma-glandular break- down (4.2%), endometrial hyperplasia (4%), iatrogenic changes (1.4%), atrophic endometrium (1.2%), and malignancy (0.1%). Endometrial polyps were detected in 14 of 33 patients with cer- vical polyps In endometrial samplings performed in patients in whom hysterectomy was planned due to myoma uteri, the most frequent diagnosis was a normal cyclic pattern (50%). In conclu- sion, in the present study, the most frequent biopsy indications of endometrial sampling were menometrorrhagia, and the most frequent histopathological diagnosis was endometrial polyp. En- dometrial polyp was also identified concomitantly in endometrial sampling of 14 out of 33 patients with cervical polyps. Thus, we concluded that in patients with an initial diagnosis of cervical polyp, the endometrium should also be evaluated.

Özet

Bu çalışmanın amacı, endometriyal örneklemin histopatolojik sonuçlarla ilişkisini değerlendirmek ve farklı yaş gruplarındaki spesifik patolojileri tanımlamaktır. Hastanemizde 2013-2014 yıl- ları arasında çeşitli nedenlerle endometrial örnekleme yapılan patoloji arşivlerinde yer alan 1374 olgunun histopatolojik sonuç- ları değerlendirildi. Biyopsi endikasyonları; menometrorrhagia (%80,5), postmenopozal kanama (%6,8), myoma uteri (%1,7), servikal polip (%2,4), infertilite (%0,2) ve hiperplazi-malignite (%8.4) idi. Histopatolojik tanılar endometrial polip (%37,2), pro- liferasyon / sekresyon / menstrüel faz (%29,3), düzensiz çoğalma endometriyumu (%8.4), yetersiz biyopsi materyali (%8.4), endo- metrit (%5.8) (% 4.2), iyatrojenik değişiklikler (%1.4), atrofik en- dometrium (%1.2), malignite (%0.1) ve endometriyum hiperplazisi (%4) izlendi. Servikal polip bulunan hastalardaki 33 endometriyal küretajın 14’ünde endometrial polip tespit edildi. Myoma uteri nedeniyle histerektomi planlanan olgularda yapılan endometri- yal örneklemelerde en sık görülen normal siklik paterndi (%50) idi. Çalışmamızda en sık görülen tanı endometrial polip olarak tanımlandı. Servikal polipin ön tanısı konan vakalarda endomet- riyumun da değerlendirilmesi gerektiği sonucuna varıldı.