The Role of Thyroid Function Tests in Prediction of the Effect of the Severity of Pre-eclampsia on Perinatal Outcomes

Abstract

INTRODUCTION:To investigate the relationship between impaired thyroidfunction testsin pregnancy and pre-eclampsia, to determine the role of this relationship in the prediction of the severity of pre-eclampsia, and to evaluate the effect on perinatal outcomes. METHODS: The study included 60 consecutive patients in the 28th-41st gestational week of a single pregnancy, diagnosed with pre-eclampsia, and a control group of 44 healthy, normotensive patients at the same stage of a single pregnancy with no medical problems. The pre-eclamptic patients were separated into two groups as severe pre-eclampsia and other preeclampsia. The groups were compared in respect of demographic data. RESULTS: This prospective, controlled study included 60 pregnant patients diagnosed with pre-eclampsia and 44 healthy pregnant patients. When the severe pre-eclampsia, other pre-eclampsia and the healthy control groups were compared in respect of thyroid function tests, TSH was determined to be statistically significantly higher in severe pre-eclampsia group than in other pre-eclampsia group and the control group (6.04 ± 9.63 μlU/ml, 2.76 ± 1.86 μlU/ml ve 2.72 ± 1.70 μlU/ml, respectively, p