Effect of Walnut or its Juice on Dyslipidemia

Osman Zikrullah ŞAHİN, Serap ŞAHİN BAYDUR, Teslime AYAZ, Neslihan ÖZYURT, Ahmet AKIN

Abstract

Background: The aim of the present study was to evaluate theeffects of walnut, walnut j uice, and diet on dyslipidemia. Methods: A total of 90 patients with dyslipidemia who appliedto our hospital were included and randomly divided into 3groups. In addition to routine diet, 30 grams of walnut were ad- ministered each morning to the 1st group, 30 grams of walnutj uice were administered to the 2nd group and a diet tailored fordyslipidemia was administered to the 3rd group. Lipid param- eters were checked after 4 weeks. Results: Mean age of patients, 55.6% of whom were femaleand 44.4% of whom were male, was 49. 1± 13.3 years. The firstlipid levels of the first group were: total cholesterol (T-chol)246±39.8 mg/dL, low-density lipoprotein (LDL) 13 1.8±30.9mg/dL, high-density lipoprotein (HDL) 44.3± 14.7 mg/dL, andtriglycerides (TG) 147±99. 1. After 4 weeks, control levels were:T-chol 242±34.4 mg/dL, LDL 134.7±28.2 mg/dL, HDL 4 1.5± 16. 1mg/dL, and TG 154±78.9 mg/dL. Difference was not statisti- cally significant (p >0.05). Lipid levels of the 2nd group were: T- chol 25 1.3±35.5 mg/dL, LDL 129.9±32.3 mg/dL, HDL 4 1.8± 13.7mg/dL, and TG 167±74.4 mg/dL. Control levels were T-chol248±36. 1 mg/dL, LDL 125.3±3 1.9 mg/dL, HDL 42.9± 14 mg/dL,and TG 174±68.7 mg/dL. Difference was not statistically sig- nificant (p >0.05). Lipid levels of the group to which the diet wasadministered were: T-chol 255.4±35. 1 mg/dL, LDL 142.5±33.7mg/dL, HDL 43.8± 17.3 mg/dL, and TG 158.8±79.6 mg/dL. Con- trol levels were: T-chol 23 1.5±25.6 mg/dL, LDL 119±28. 1 mg/ dL, HDL 44. 1± 15.2 mg/dL, and TG 140.5±63.4 mg/dL. Differ- ence was statistically significant (p >0.05). Conclusion: More ex tensive studies are needed to j udge thesuitability of walnut in treating dyslipidemia. Results demon- strate that diet is still the best treatment.

Özet

Amaç: Bu çalışmada dislipidemi tedavisinde ceviz, cevizsuyu kürleri ve diyetin etkilerinin karşılaştırılması amaçlandı. Gereç ve Yöntem: Hastanemize başvuran, dislipidemisi olan90 hasta araştırmamıza alındı. Rastgele 30arlı üç grup oluş- turuldu. Alışılmış diyete ek olarak, birinci gruba her sabah 30gram ceviz yemeleri, ikinci gruba her sabah 30 gr ceviz suyuiçmeleri ve üçüncü gruba dislipidemi diyeti önerildi. Dörthafta sonra lipid parametreleri kontrol edildi. Bulgular: %55.6sı kadın %44.4ü erkek olan hastaların or- talama yaşı 49.1±13.3 idi. Ceviz kürü verilen grubun çalışmabaşında alınan ilk lipid düzeyleri sırasıyla total kolesterol:246±39.8 mg/dl, LDL-k: 131.8±30.9 mg/dl, HDL: 44.3±14.7mg/dl, TG: 147±99.1 olarak bulundu. Dört hafta sonra alınankontrol düzeyleri; T-chol: 242±34.4 mg/dl, LDL-k: 134.7±28.2mg/dl, HDL: 41.5±16.1 mg/dl, TG: 154±78.9 mg/dl idi. Arada- ki fark istatistiksel olarak anlamlı değildi (p>0.05). Ceviz suyuiçen grubun ilk bakılan lipid düzeyleri; T-chol: 251.3±35.5mg/dl, LDL-k: 129.9±32.3 mg/dl, HDL: 41.8±13.7 mg/dl, TG:167±74.4 mg/dl olarak bulundu. Kontrol değerler; T-chol:248±36.1 mg/dl, LDL: 125.3±31.9 mg/dl, HDL: 42.9±14 mg/ dl, TG: 174±68.7mg/dl olup aradaki fark istatistiksel olarakanlamlı değildi (p>0.05). Sadece diyet önerdiğimiz grubunilk bakılan lipid düzeyleri; T-chol: 255.4±35.1mg/dl, LDL-k:142.5±33.7 mg/dl, HDL: 43.8±17.3 mg/dl, TG: 158.8±79.6 mg/ dl olup, kontrol değerler; T-chol: 231.5±25.6 mg/dl, LDL-k:119±28.1 mg/dl, HDL: 44.1±15.2 mg/dl, TG: 140.5±63.4 mg/dlolup aradaki fark istatistiksel olarak anlamlı bulundu (p