Determination of risk factors and perinatal outcomes of singleton pregnancies complicated by isolated single umbilical artery in Turkish population

Abstract

Objective: To address the possible risk factors, eventual pregnancy outcomes, and probable troubles in follow-ups of pregnancies complicatedby an isolated single umbilical artery and to provide data on Turkish cases in such an aspect that ethnic divergences may have influence.Material and Methods: A total of 16568 singleton pregnancies that were delivered between May 2006 and May 2013 were retrospective -ly screened. Ninety-three fetuses were found to have an isolated single umbilical artery. One-hundred pregnancies that did not show anystructural or chromosomal abnormalities were randomly selected from the rest of the cases to establish the control group. IBM SPSS Statis -tics 20.0 software was utilized for statistical analysis. Non-parametric data were analyzed with Mann-Whitney U test and were presented asmeans±standard deviations. P values less than 0.05 were statistically significant. For the adjustment of confounding factors, odds ratios (ORs)and 95% confidence intervals (CIs) were estimated by multiple logistic regression analysis.Results: The incidence of small for gestational age (SGA) fetuses and hypertensive disorders in pregnancy was found to be significantly higherin cases with an isolated single umbilical artery (p