Journals / Journal of the Turkish Chemical Society, Section A: Chemistry / 2017 / Cilt: 4 - Sayı: 3
The Spectroscopic and Thermal Properties, Antibacterial and Antifungal Activity and DNA Interactions of 4- (Fluorobenzyl)Spiro(N/O) Cyclotriphosphazenium Salts
- Pages
- 993–1016
- DOI
- —
Abstract
The protic ionic liquids (PILs) (3a-3d) weresynthesized from the reactions of tetraamino-4-(fluorobenzyl)spiro(N/O)cyclotriphosphazenes(2a-2d) with gentisic acid in dry THF. The structures of thePILswere verifiedby the elemental analyses, Fourier transform infrared (FTIR), 1H, 13C{1H}and31P{1H} NMR techniques.The thermal properties of the PILswere evaluated using TG/DTG/DTA instrument.The antifungal and antibacterialactivityof the PILswere examined against somefungi and bacteria,and theseobtained results were compared with the evaluations of the corresponding fully substituted cyclotriphosphazene bases. The interactions between thePILsandsupercoiled PBR322DNA were scrutinized,and it was determined that they exhibited significant conformational changes