Journals / Journal of the Turkish Chemical Society, Section A: Chemistry / 2019 / Cilt: 6 - Sayı: 3
Anticancer Activities of Even-Numbered Monoketo Eicosanoic Acid Anilides and Semicarbazones
- Pages
- 429–432
- DOI
- —
Abstract
This work was carried out on the cytotoxic activity of semicarbazone and anilide derivatives ofketoeicosanoic acids on canine mammary tumor cell line (CMT-U27). Five semicarbazone compounds (1-5) and five anilide compounds (6-10) were used in this study. 8-Semicarbazone eicosanoic acid (3) wasshown to be cytotoxic. In contrast, 10-keto eicosanoic acid anilide (9) has been shown to be lesscytotoxic towards CMT-U27 cell line.