Synthesis of Polysulfone Based Amphiphilic Graft Copolymers by a ‘Grafting to’ Approach

Abstract

Synthesis of amphiphilic polysulfone graft copolymers by ‘‘Click’’ chemistry is described. First, acommercial PSU was chloromethylated to give chloro-funtional PSU (PSU-Cl). Subsequently, chloridegroups were converted into azide moieties by nucleophilic substitution. Hydrophilic poly(N,Ndimethylacrylamide) (PDMA) side chains were then attached via a “grafting to” approach by using coppercatalyzed azide–alkyne cycloaddition (CuAAC). Precursor polymer and the final amphiphilic copolymerswere characterized by proton nuclear magnetic resonance (1H NMR), fourier-transform infraredspectroscopy (FT-IR), gel permeation chromatography (GPC) and contact angle measurements.