Rapid onset of pedal edema associated with risperidone in two male patients: simultaneous clinical cases

Abstract

Pedal edema due to drugs is common especially with beta blockers, calcium channel blockers, non-steroidal antiinflammatorydrugs, and several hormonal drugs but they can rarely occur with new generation atypical antipsychotics.There are case reports with risperidone especially as peripheral edema. We present two male patients (Case A: 51-yearold,diagnosed with bipolar disorder type 2; Case B: 55-year-old, diagnosed with psychotic disorder plus mild mentalretardation) who developed bilateral pedal edema after treatment with risperidone. Risperidone treatment in the elderlyshould be carefully decided because even small doses of risperidone may increase risk of edema.