New Insight of Tumor Microenvironment in Non-Small Cell Lung Cancer

Abstract

As in all living cells, cancer cells are evaluating is very important in the frames of tumor development and treatment. As in all evolutionaryprocess, the environment of living cells has an important role. Tumor cells have an environment is called tumor microenvironment, affectsthe therapeutic response and clinical results. Tumor microenvironments involve various cell types, extracellular matrix substances that arein the niche of cancer cells. The microenvironment is not only important in tumorigenesis but it is effective on therapeutic efficacy. In thisreview, we carried out the interaction between non-small cell lung cancer and its microenvironment to point out the significance of the tumorenvironment.