IMPORTANCE OF DIFFERENT CHARACTERISTIC OF THE CORTICOSPINAL TRACT BASED ON TRACTOGRAPHY AND CADAVERIC MICRODISSECTION

Abstract

Purpose: Microsurgical anatomy of the corticospinal tract, its functional role and crucial points indifferential diagnosis were evaluated. There is no consensus about its differences and cerebral origin ofthe corticospinal tract. Tractography and cadaver dissection can help to investigate the characteristics ofthe corticospinal tract. Also, amyotrophic lateral sclerosis is hard to diagnose as it has common symptomsand signs with other disorders.Methods: Three formalin-fixed human brains (six sides) were dissected by the Klingler technique in astepwise manner from the lateral to medial and superior to inferior under 6x–40x magnification using asurgical microscope. All stages of the dissection were photographed using three-dimensional method.Lastly, we present a patient with the sign of drop foot who underwent electromyographical and radiologicalexamination, diagnosed as atypic amyotrophic lateral sclerosis.Results: The connections of the corticospinal tract, in particular the travel in the in trajectories of stepwisein manner cerebral origin. We demonstrated a case report with anatomic correlation to define the damageof corticospinal tract in variable levels. Crucial landmarks, connections, eloquent brain areas that relatedto the corticospinal tract were emphasized.Conclusion: So that pointing the importance of such disorders to keep in mind as not to move forwardwith incorrect operation decision. Trajectory of one of the largest desending pathway, corticospinal tractand the relationship with different diagnosis should be considered.