ORGANOID AS A NOVEL TECHNOLOGY FOR DISEASE MODELING

Abstract

The organoid technology is capable to create more real-like in vitro models in terms of structure andfunction of the origin of the tissue. Since the three-dimensional model is able to illustrate diseasepathology, cell differentiation, and recapitulation of self-renewal, lead organoid technology as a promisingdisease model to fill the gap between conventional two-dimensional, and in vivo disease models. Thereview describes the recent development of organoid disease modeling approaches.