Journals / İzmir Atatürk Eğitim Hastanesi Tıp Dergisi / 2008 / Cilt: 46 - Sayı: 1
The comparative prevalence of susceptibility to glycopeptide antiibiotics of methicillin - resistant strains of staphylococci isolated in İzmir Atatürk Training Hospital
- Pages
- 35–38
- DOI
- —
Abstract
Methicillin - resistant strains of Staphylococcus aureus (MRSA) and Methicillin-resistant coagulase-negative Staphylococci (MRCoNS) isolated from patients, being infected or colonized, were examined. Their susceptibility to glycopeptide antibiotics (vancomycin, teicoplanin) were evaluated by the procedure outlined by the National Committee for Clinical Laboratory Standards using disk agar diffusion method. In our study, 70 of 100 Staphylocci isolates were MRSA (70 %) and 30 were MRCoNS (30 %). 83 of them had been isolated from clinical materials and 17 had been from outpatients. 58 of total 83 clinical isolates were MRSA (69.9 %) and 25 were MRCoNS (30.1 %). 12 of 17 Methicillin - resistant Staphylococci isolated from outpatients were MRSA (70.6 %) and 5 of them were MRCoNS (29.4 %). In 3 strains (2 MRSA / 1 MRCoNS) of the total 100 Methicillin - resistant Staphylococci, it was seen that susceptibility to teicoplanin was decreased (≤ 14 mm) and susceptibility to vancomycin was high in all.
Özet
Stafilococus aureusun metisiline dirençli (MRSA) ve metisilin dirençli koagülaz negatif stafilokok (MRKNS) kökenleriyle enfekte veya kolonize olmuş hastalardan izole edilen suşlar incelendi. Glikopeptid antibiotiklere (vancomycin, teicoplanin) duyarlılıkları NCCLS'nin standartları doğrultusunda disk agar difüzyon yöntemi ile saptandı. Çalışmamızda 100 Stafilokok izolatinin 70'I MRSA (% 70), 30'u MRKN Stafilokok'tu (% 30) MR Stafilokokların 83'ü kliniklerden, 17'si polikliniklerden gelen materyallerden izole edildi. 83 klinik izolatın 58'I (% 69.9) MRSA, 25'I (% 30.1) MRKN Stafilokok, polikliniklerden gelen 17 Metisilin dirençli Stafilokok'un 12'si (% 70.6) MRSA, 5'I (% 29.4) MRKN Stafilokok idi. Toplam 100 adet Metisilin dirençli Stafilokoktan 3'ünde (2 MRSA/1 MRKNS) teicoplanine duyarllığın azaldığı ≤ 14mm, vancomycin duyarllığının ise hepsinde yüksek olduğu gözlendi.