The influence of bone and muscle mass on varus osteoarthritis of the knee

Abstract

We studied 50 knees of 25 women patients with bilateral varus Osteoarthritis of the knee to determine the relationship between the bone mineral density (BMD), body-mass index (BMI) and varus deformity. The mean age of patients were 66,6. Four angles were measured to assess the varus deformity of each knee: The femorotibial (FT) angle, the femoral condylar-femoral shaft (FC-FS) angle, the femoral condylar-tibial plateau (FC-TP) angle, the tibial plateau-tibial shaft (TP-TS) angle. The FC-FS/FT, FC-TP/FT and TP-TS/FT angles were also calculated to determine which component angle was predominant in the varus deformity. BMD of the L2-L4 spinal region was measured, by dual photon x-ray absorptiometry. Body-mass index (BMI), an indicator of obesity, was calculated. BMD/BMI was also calculated to determine the influence of body mass on BMD. In statistical evaluation of results a correlation was found between severity of varus osteoarthritis and low BMD and BMD/BMI (r= -0.486, p

Özet

Bilateral varus diz osteoartritine sahip 25 bayan hastanın 50 dizi, varus deformitesi ile kemik düz graf condylar-tibial plateau (FC-TP) angle, the tibial plateau-tibial shaft (TP-TS) angle. The FC-FS/FT, FC-TP/FT and TP-TS/FT angles were also calculated to determine which component ilerde; femorotibial (FT) açı, femoral kondil-femoral şaft (FK-FŞ) açısı, femoral kondil-tibia plato (FT-TP) açısı, tibial plato-tibial şaft (TP-TŞ) açısı hesaplandı. Varus deformitesi üzerinde hangi komponentin etkili olduğunu belirlemek üzere FK-FŞ/FT, FK-TP/FT ve TP-TŞ/FT oranları hesaplandı. L2-L4 vertebral bölgenin kemik mineral yoğunluğu (KMY), DEXA yöntemi ile ölçüldü. Şişmanlığın bir göstergesi olarak vücut-kas indexi (VKİ)00ve KMY/VKİ hesaplanarak KMY üzerinde vücut kas kitlesinin etkisi hesaplandı. Varus diz osteoartriti ile düşük KMY ve KMY/VKİ değerleri arasında korrelasyon me0--ttu (r= -0.486, p