Effect of blood transfusion on liver transplant’s outcomes and predictive factors on transfusion

Karaciğer nakli sonuçları üzerinde kan transfüzyonlarının etkisi ve transfüzyon gereksinimini etkileyen faktörler

Ömer AYANOĞLU, Murat DAYANGAC, Deniz BALCI, Cihan DURAN, Yıldıray YÜZER, Onur YAPRAK, Süleyman URAZ, Yaman TOKAT

Abstract

BACKROUND: The aim of this study is to identify the preoperative variables associated with prediction of intraoperative blood transfusion as well as analyze the influence of intraoperative blood transfusion on postoperative outcomes. MATERIALS and METHOD: Between June 2004 and May 2006 a total of 81 liver transplantation (16 CDLT, 65 LDLT) were performed on 81 patients (56 male and 25 female) who had end stage liver at our hospital. The patients were split in two groups, as similar previous studies. High transfusion group (HTG) (>4 RBC) was compaired againts the low transfusion group (LTG) (< 4RBC). Univariate analysis was performed with the independent student’s t- test for quantitative variables and chi-square test was used for qualitative variables after data categorization and calculation. RESULTS: The mean transfused units of red blood cell (RBC) was 5.41. Patient’s age, availabity of HCV and elevated Child score had significance for intraoperative blood transfusion requirement. Postoperative mortality and reoperation rate had significantly elevated in HTG patients also HTG patients had more infectious. CONCLUSION: We concluded that high blood transfusion has major effect on posttransplant complications and postoperative mortality

Özet

AMAÇ: İntraoperatif kan transfüzyon ihtiyacı üzerindeki preoperatif hasta karekteristiklerinin etkisini araştırmak ve aynı zamanda kan transfüzyonunun postoperatif mortalite ve morbiditeye etkilerini değerlendirmek. MATERYAL ve METOD: Haziran 2004 ile Mayıs 2006 tarihleri arasında kliniğimizde son evre karaciğer hastalığı olan 16’sı kadaverik ve 65’i canlıdan olmak üzere toplam 81 hastaya karaciğer transplantasyonu uygulandı. Hastalar daha önceki çalışmalarda olduğu gibi 2 gruba ayrıldı). Yüksek transfüzyon yapılmış gurup (YTG) (>4 ünite eritrosit süspansiyonu) ve düşük transfüzyon yapılmış gurup (DTG) (