Helicobacter pylori: Precipitating factors and seroprevalence in children

Abstract

This study was performed to investigate the prevalence of Helicobacter pylori infection and cagA as well as factors affecting this prevalence in 235 children. ELISA was used for determining the seroprevalence of special IgG and cagA. Seropositiveness of H. pylori infection was 34.9% in children. Seropositiveness of cagA was 20.7% in children in whom H. pylori IgG was positive. It was found that there was no statistical difference in the seroprevalence of H. pylori and cagA when gender and age groups were compared. The ratios of seropositivity of mumps and respiratory syncytial virus infection were 43.4% and 86%, respectively. Although there was a significant difference between the serology of the respiratory sinsitial virus and H. pylori (p

Özet

Helicobacter pylori ve cagA prevalansını belirlemek ve buna etki eden faktörleri saptamak amacıyla toplam 235 çocukta yapılan bu çalışmada özgül IgG'ler ve cagA seroprevalansının saptanmasında ELISA kullanılmıştır. Çocuklarda H. pylori seropozitifliği %34.9 (82/235) ve H. pylori IgG'si pozitif olanlarda saptanan cagA seropozitifliği %20.7 (17/82)'dir. Helicobacter pylori ve cagA seroprevalansının yaş grupları ve cinsiyete göre istatistiksel olarak farklılık göstermediği görülmüştür. Kabakulak ve solunum sinsityal virus seropozitiflik oranları %43.4 ve %86'dır. Solunum sinsityal virus ve H. pylori serolojisi arasında anlamlı derecede farklılık (p