Preparation, Characterization and Evaluation of Some New Amides as Antimicrobial Agents

Abstract

The some new amide derivatives 1(a-c) and, 2d were synthesized by the two-step N-acylation of 4-nitroaniline or heterocyclic amine derivatives with acyl chlorides. All of the products were determined using 13C NMR, 1H NMR, FT-IR spectroscopies and elemental analysis. Antimicrobial activities of the molecules were evaluated against various bacterial and fungal species. The results show that the some new compounds exhibit good antibacterial and antifungal activities.