Comparison of Ibuprofen Protocols in the Pharmacological Treatment of Patent Ductus Arteriosus

Abstract

Introduction: Ibuprofen (IBU) is an effective agent for the pharmacological treatment of patent ductus arteriosus (PDA) in premature infants. In this study, we compared the efficacy and complications of intravenous bolus therapy (IVBT) and con- tinuous intravenous infusion therapy (CIVIT) for the treatment of PDA. Methods: The study was conducted with 64 preterm infants in neonatal intensive care unit with gestational age