Could Neutrophil-Lymphocyte Ratio or Platelet Lymphocyte Ratio Have a Role in Urgent Dialysis Decision?

Abstract

Introduction: Chronic kidney disease (CKD) is the chronic and progressive deterioration of metabolic and endocrine functions together with the inability to adjust the fluid-solute balance of the kidney. In our study, the values of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) before and after dialysis were compared in patients with chronic renal failure, except for patients with infection clinic admitted to the emergency department. Our aim is to examine the changes in the parameters of complete blood count (hemogram) before and after dialysis, which is a fast and inexpensive test, to discuss whether these changes will give an idea in determining the need for urgent dialysis. Methods: The CKD patients who received a routine dialysis program in the Nephrology Clinic Dialysis Unit of Istanbul Haydarpaşa Numune Training and Research Hospital were examined. Among the patients with CKD who received routine dialysis in our hospital, patients who presented to the emergency department for various reasons between January 2016 and January 2018 were included in our study. Laboratory examinations were made with MINDRAY BC6800 brand hemogram device. As a statistical analysis, the mean values, standard deviations, median values of the data were calculated. Student’s t-test was used to compare the Chi-square test variants. Results: Between January 2016 and January 2018 a total of 458 CKD patients applied to our emergency department. The pre-dialysis and post-dialysis NLR ratios of the patients show a statistically significant change in all age groups (p