The detection of the genotoxic effects of some nitro aromatic compounds by the allium test system

Abstract

Three nitroarenes were investigated by using Allium test on the root tips of Allium cepa L. Root tips were treated with different series of concentrations of 4- nitro-ophenylenediamine, 2,4-diaminophenoldihydrochloride and 4-nitroquinoline-1 - oxide (4-NQO) ranging from 6.5x$10^{-3}$ - 6.5x $10^{-8}$ -M, 5x$10^{-3}$ -5x$10^{-8}$ M and 1x$10^{-3}$ - 1x$10^{-12}$ M respectively. Used nitroarenes caused decrease in the Mitotic index (MI) and increase frequency of abnormal mitosis when compared with the control.