Mixed connective tissue disease previously misdiagnosed as various disorders

Abstract

Mixed connective tissue disease is an autoimmune multisystemic disease which is presented rarely in the childhood period. It is characterised by overlapping clinical features similar to those of SLE, Scleroderma and Polymyositis/Dermatomyositis and very high titers of circulating antinuclear antibody to a nuclear ribonucleoprotein (RNP) antigen. Hence it can be sometimes misdiagnosed as JRA, SLE or Scleroderma. This case is reported both becouse of this property and rare presentation in the childhood period.