Oligoasthenozoosspermia with rare karyotype

Abstract

In a couple who had been investigated because of infertility, oligo-asthenozoospermia was diagnosed in man, by sperm analysis. Cytogenetic analyse, the karyotype of man was exhibited as 46,XY, t(9;15) (pter ›q21.1::q11.1›qter), der (9) (ptel›q21.1), whereas his wife's was 46,XX. To our knowlodge, this is the first case, which was determined by conventional cytogenetic techniques, reported in the literature associated with severe male infertility. The degree of the efficiency of this rare karyotype on abortions and genetic counselling period that includes evaluating the view of unbalanced segragations of this karyotype was argued based on the literature.