Comparison of Retinal Nerve Fiber Layer Parameters Obtained Using Optical Coherence Tomography and Standard Automated Perimetry Results in Patients with Initial Diagnosis of Suspected Glaucoma

Abstract

Purpose: To determine the relationship between retinal nerve fiber layer (RNFL) parameters obtained using optical coherence tomography (OCT) and the outcomes of standard automated perimetry (SAP) in patients with initial diagnosis of suspected glaucoma. Materials and Methods: We retrospectively reviewed data of 147 eyes of 74 patients (aged 30-70 years) who were initially diagnosed as suspected glaucoma at ophthalmology outpatient clinic by an ophthalmologist between January 2017 and December 2019 and had at least six months of follow-up. We compared outcomes of visual field (VF) testing and RNFL thickness as measured by OCT, when available. We noted eyes diagnosed as glaucoma during follow-up.. Results: There were no significant correlations between SAP findings (Mean Deviation (MD), Pattern Standard Deviation (PSD)), and RNFL thickness (Mean, inferior, superior, nasal, temporal RNFL) obtained by using OCT (Spearman’s rho p>0,05) in patients with initial diagnosis of suspected glaucoma. Conclusions: In our study, no signi ficant correlation was found between VF findings and OCT parameters in patients with initial diagnosis of suspected glaucoma. Given the clinical presentation of these patients, it is important to assess the VF and OCT evaluations together in these patients in order to make definitive diagnosis.