Evaluation of P-Wave Dispersion, Ventricular Functions, and Atrial Electromechanical Coupling in Children with Type 1 Diabetes Mellitus

Abstract

Objective: The present study aimed to evaluate ventricular diastolic function, inter- and intra-atrial conduction delay, and P wavedispersion in pediatric patients with type 1 diabetes mellitus (DM).Methods: This study comprised 30 pediatric patients with type 1 DM and 30 healthy children served as the control group. P wavedispersion (Pd )was measured on a 12-channel ECG. Both systolic and diastolic functions of both ventricles were evaluated usingconventional and tissue doppler imaging (TDI) echocardiography (ECHO). Atrial electromechanical delay was measured using TDIaccompanied with electrocardiography (ECG).Results: On conventional transthoracic echocardiography (ECHO), the mitral E/A ratio and isovolumetric relaxation times (IVRT)were different between the patients with type 1 DM and the control group (1.67±0.46 vs. 1.95±0.43, p=0.017 and 74.5±7.0 vs.63.3±5.2, p