Encapsulated Papillary Carcinoma in A Man with Gynecomastia: Ultrasonography, Mammography and Magnetic Resonance Imaging Features with Pathologic Correlation

Abstract

Male breast cancer is an uncommon disease that constitutes 1% of all breast cancers and encapsulated papillary carcinoma (EPC) is a raresubtype of malignant male diseases. Gynecomastia is the most common disease of the male breast. We report a 63-year-old male patientwith EPC accompanied by gynecomastia that was diagnosed and treated at our breast center. Mammography showed an oval-shaped densemass with circumscribed margins on the ground of nodular gynecomastia. On ultrasonographic exam, we saw a well-circumscribed complexmass with a solid component which was vascular on Doppler ultrasonography. Magnetic resonance imaging revealed a complex cysticmass containing solid components. Dynamic images showed enhancement of the cystic mass wall and mural components. Tumor stagewas evaluated as T2N0. The lesion’s histologic examination and immunohistochemical analysis by showing no myoepithelial layer revealedan encapsulated papillary carcinoma. To our knowledge, this is the first case report which describes MR imaging findings of male breastencapsulated papillary cancer